Rivaroxaban-d4(Synonyms: BAY 59-7939-d4)

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Rivaroxaban-d4 (Synonyms: BAY 59-7939-d4) 纯度: 98.51%

Rivaroxaban D4 (BAY 59-7939 D4) 是 Rivaroxaban 的氘代物。Rivaroxaban 是一种高效，选择性凝血因子 Xa (FXa) 抑制剂，IC50 为 0.7 nM，Ki 为 0.4 nM。

Rivaroxaban-d4(Synonyms: BAY 59-7939-d4)

Rivaroxaban-d4 Chemical Structure

CAS No. : 1132681-38-9

规格 价格 是否有货 数量
1 mg ￥3500 In-stock
5 mg ￥9800 In-stock
10 mg ￥15800 In-stock
50 mg   询价  
100 mg   询价  

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生物活性

Rivaroxaban D4 (BAY 59-7939 D4) is a deuterium labeled Rivaroxaban. Rivaroxaban is a highly potent，selective and direct Factor Xa (FXa) inhibitor, achieving a strong gain in anti-FXa potency (IC50 0.7 nM; Ki 0.4 nM)[1][2].

IC50 & Target

IC50: 0.7 nM (Factor Xa); Ki: 0.4 nM (Factor Xa)[1][2]
分子量

439.91

Formula

C19H14D4ClN3O5S
CAS 号

1132681-38-9
中文名称

利伐沙班 d4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
参考文献

  • [1]. Roehrig S, et al. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19)

    [2]. Perzborn E, et al. In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939–an oral, direct Factor Xa inhibitor. J Thromb Haemost. 2005 Mar;3(3):514-21.

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