Levamlodipine-d4(Synonyms: (S)-Amlodipine-d4; Levoamlodipine-d4)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Levamlodipine-d4 (Synonyms: (S)-Amlodipine-d4; Levoamlodipine-d4)

Levamlodipine-d4 ((S)-Amlodipine-d4) 是 Levamlodipine 的氘代物。Levamlodipine ((S)-Amlodipine) 是一种功能强大的二氢吡啶钙通道 (calcium channel) 阻滞剂，具有舒张血管的作用，可用于高血压、心绞痛的研究。

Levamlodipine-d4(Synonyms: (S)-Amlodipine-d4; Levoamlodipine-d4)

Levamlodipine-d4 Chemical Structure

CAS No. : 1346617-19-3

规格 是否有货
5 mg Check price and availability

* Please select Quantity before adding items.

生物活性

Levamlodipine-d4 ((S)-Amlodipine-d4) is the deuterium labeled Levamlodipine. Levamlodipine ((S)-Amlodipine) is a powerful dihydropyridine calcium channel blocker, possessing vasodilation properties and used in the treatment of hypertension and angina[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

412.90

Formula

C20H21D4ClN2O5
CAS 号

1346617-19-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Jain R, et al. Polyaniline-graphene oxide nanocomposite sensor for quantification of calcium channel blocker levamlodipine. Mater Sci Eng C Mater Biol Appl. 2016 Aug 1;65:205-14.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务