Octopamine-d4 hydrochloride(Synonyms: (±)-p-Octopamine-d4 hydrochloride)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Octopamine-d4 hydrochloride (Synonyms: (±)-p-Octopamine-d4 hydrochloride)

Octopamine-d4 ((±)-p-Octopamine-d4) hydrochloride 是 Octopamine hydrochloride 的氘代物。Octopamine ((±)-p-Octopamine) hydrochloride 是一种与去甲肾上腺素结构相关的生物单胺类物质，在无脊椎动物中起着神经激素、神经调节剂和神经递质的作用。Octopamine hydrochloride 对转染人 alpha2-肾上腺素受体(ARs) 的中国仓鼠卵巢细胞 α2-ARs 有刺激作用。Octopamine hydrochloride 增加糖原分解、糖酵解、摄氧量、糖异生和门脉灌注压。

Octopamine-d4 hydrochloride(Synonyms: (±)-p-Octopamine-d4 hydrochloride)

Octopamine-d4 hydrochloride Chemical Structure

CAS No. : 1219803-62-9

规格 是否有货
100 mg   询价  
250 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

生物活性

Octopamine-d4 ((±)-p-Octopamine-d4) hydrochloride is the deuterium labeled Octopamine hydrochloride. Octopamine ((±)-p-Octopamine) hydrochloride, a biogenic monoamine structurally related to noradrenaline, acts as a neurohormone, a neuromodulator and a neurotransmitter in invertebrates. Octopamine hydrochloride can stimulate alpha2-adrenoceptors (ARs) in Chinese hamster ovary cells transfected with human alpha2-ARs. Octopamine hydrochloride increased glycogenolysis, glycolysis, oxygen uptake, gluconeogenesis and the portal perfusion pressure[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

192.66

Formula

C8H9D3ClNO2
CAS 号

1219803-62-9
中文名称

章胺盐酸盐 d4 (盐酸盐)
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Farooqui T. Octopamine-mediated neuromodulation of insect senses. Neurochem Res. 2007;32(9):1511-1529.

    [3]. Roeder T. Octopamine in invertebrates. Prog Neurobiol. 1999;59(5):533-561.

    [4]. Axelrod J, et al. Octopamine. Nature. 1977;265(5594):501-504.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务