Palmitic acid-15,15,16,16,16-d5(Synonyms: 棕榈酸 d5)

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Palmitic acid-15,15,16,16,16-d5 (Synonyms: 棕榈酸 d5)

Palmitic acid-15,15,16,16,16-d5 是 Palmitic acid 的氘代物。Palmitic acid 是一种常见于动物和植物中的长链饱和脂肪酸。Palmitic acid 可以诱导小鼠颗粒细胞中葡萄糖调节蛋白 78 (GRP78) 和 CCAAT/增强子结合蛋白同源蛋白 (CHOP) 的表达。

Palmitic acid-15,15,16,16,16-d5 Chemical Structure

CAS No. : 285979-77-3

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生物活性	Palmitic acid-15,15,16,16,16-d5 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	261.45
Formula	C₁₆H₂₇D₅O₂
CAS 号	285979-77-3
中文名称	棕榈酸 d5
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Harada H, et al. Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga. Anticancer Res. 2002 Sep-Oct;22(5):2587-90.

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