Taurine-13C2(Synonyms: 2-Aminoethanesulfonic acid-13C2)

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Taurine-13C2 (Synonyms: 2-Aminoethanesulfonic acid-13C2)

Taurine-13C2 (2-Aminoethanesulfonic acid-13C2) 是一种 13C 标记的 Taurine。Taurine 是一种含硫氨基酸和一种参与细胞体积调节的有机渗透剂，为胆汁盐的形成提供底物，并在调节细胞内游离钙浓度方面发挥作用。Taurine 有激活脂肪细胞自噬 (autophagy) 的能力。

Taurine-13C2(Synonyms: 2-Aminoethanesulfonic acid-13C2)

Taurine-13C2 Chemical Structure

CAS No. : 70155-54-3

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生物活性

Taurine-13C2 (2-Aminoethanesulfonic acid-13C2) is the 13C-labeled Taurine. Taurine, a sulphur-containing amino acid and an organic osmolyte involved in cell volume regulation, provides a substrate for the formation of bile salts, and plays a role in the modulation of intracellular free calcium concentration. Taurine has the ability to activate autophagy in adipocytes[1][2][3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

127.13

Formula

13C2H7NO3S
CAS 号

70155-54-3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Ripps H, Shen W. Review: taurine: a “very essential” amino acid. Mol Vis. 2012;18:2673-2686.

    [3]. Xu YJ, et al. The potential health benefits of taurine in cardiovascular disease. Exp Clin Cardiol. 2008;13(2):57-65.

    [4]. Kaneko H, et al. Taurine is an amino acid with the ability to activate autophagy in adipocytes. Amino Acids. 2018;50(5):527-535.

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