Leucinostatin A (Synonyms: Antibiotic P168)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Leucinostatin A (Synonyms: Antibiotic P168)

Leucinostatin A (Antibiotic P168) 是一种九肽，对白色念珠菌和新型隐球菌具有显着的活性。 Leucinostatin A 是一种疏水性九肽抗生素。Leucinostatin A 通过减少前列腺基质细胞中胰岛素样生长因子-I 的表达来抑制前列腺癌的生长。具有抗原虫活性。

Leucinostatin A Chemical Structure

CAS No. : 76600-38-9

规格	价格	是否有货	数量
500 μg	￥3780	3 – 4 周

* Please select Quantity before adding items.

Leucinostatin A 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性	Leucinostatin A (Antibiotic P168) is a nonapeptide exerting a remarkable activity especially against Candida albicans and Cryptococcus neoformans. Leucinostatin A is a hydrophobic nonapeptide antibiotic. Leucinostatin A inhibits prostate cancer growth through reduction of insulin-like growth factor-I expression in prostate stromal cells. Antiprotozoal activies^[1].
分子量	1218.61
Formula	C₆₂H₁₁₁N₁₁O₁₃
CAS 号	76600-38-9
Sequence Shortening	P-{Nva}-L-{Aib}-LL-{Aib}-{Aib}-{Bal}
结构分类	Others
初始来源	微生物 Paecilomyces lilacinus
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料	Data Sheet (526 KB) 产品使用指南 (1538 KB)
参考文献	[1]. Csermely P, et al. The nonapeptide leucinostatin A acts as a weak ionophore and as an immunosuppressant on T lymphocytes. Biochim Biophys Acta. 1994;1221(2):125-132. [Content Brief] [2]. Ricci M, et al. Leucinostatin-A loaded nanospheres: characterization and in vivo toxicity and efficacy evaluation. Int J Pharm. 2004;275(1-2):61-72. [Content Brief] [3]. Brand M, et al. Antiprotozoal Structure-Activity Relationships of Synthetic Leucinostatin Derivatives and Elucidation of their Mode of Action. Angew Chem Int Ed Engl. 2021;60(28):15613-15621. [Content Brief]

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务