上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Neogambogic acid
Neogambogic acid 是藤黄的有效成分,可诱导细胞凋亡并具有抗癌作用。Neogambogic acid 对耐甲氧西林的金黄色葡萄球菌 (MRSA) 具有明显的抑制活性。
Neogambogic acid Chemical Structure
CAS No. : 93772-31-7
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生物活性 |
Neogambogic acid, an active ingredient in garcinia, induces apoptosis and has anticancer effect. Neogambogic acid has significant inhibitory activity toward methicillin-resistant Staphylococcus aureus (MRSA)[1][2]. |
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体外研究 (In Vitro) |
Neogambogic acid inhibits HCT-8, Bel-7402, BGC-823, A549, and A2780 cell proliferation, with an IC50 between 1.75 and 3 μM. Neogambogic acid induces A549 cells apoptosis arrested the cells to G0/G1 phase in vitro[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
体内研究 (In Vivo) |
Neogambogic acid arrests A549-induced tumor growth in nude mice[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
分子量 |
646.77 |
Formula |
C38H46O9 |
CAS 号 |
93772-31-7 |
结构分类 |
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初始来源 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
纯度 & 产品资料 |
Data Sheet (529 KB) 产品使用指南 (1538 KB)
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参考文献 |
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