O-Nornuciferine (Synonyms: O-去甲荷叶碱)

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O-Nornuciferine  (Synonyms: O-去甲荷叶碱) 纯度: 99.89%

O-Noruciferine 是荷叶的一种卟啉型生物碱，是一种有效的 hERG 通道抑制剂。

O-Nornuciferine (Synonyms: O-去甲荷叶碱)

O-Nornuciferine Chemical Structure

CAS No. : 3153-55-7

规格 价格 是否有货 数量
1 mg ￥1400 In-stock
5 mg ￥3500 In-stock
10 mg ￥5500 In-stock
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O-Nornuciferine 相关产品

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生物活性

O-Nornuciferine, an aporphine-type alkaloid from lotus leaf, is a potent hERG channel inhibitor[1].

体外研究
(In Vitro)

O-Nornuciferine has an IC50 of 7.91 μM in vitro hERG blockages measured in HEK293 cells[1].
O-Nornuciferine (100 μM) has 47% hERG channel inhibition in Xenopus oocytes by lotus alkaloids[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

O-Nornuciferine 相关抗体:
分子量

281.35

Formula

C18H19NO2
CAS 号

3153-55-7
性状

固体

颜色

White to off-white

中文名称

O-去甲荷叶碱
结构分类
  • Alkaloids
  • Isoquinoline Alkaloids
  • Phenols
  • Monophenols
初始来源
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

溶解性数据
In Vitro: 

DMSO 中的溶解度 : 50 mg/mL (177.71 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.5543 mL 17.7715 mL 35.5429 mL
5 mM 0.7109 mL 3.5543 mL 7.1086 mL
10 mM 0.3554 mL 1.7771 mL 3.5543 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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浓度

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

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体积 (start)

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浓度 (final)

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体积 (final)

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动物溶解方案

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给药剂量

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计算结果
工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: 99.89%

Data Sheet (600 KB) SDS (251 KB)

COA (271 KB) HNMR (249 KB) LCMS (264 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Ulrike Grienke, et al. Human Ether-à-go-go Related Gene (hERG) Channel Blocking Aporphine Alkaloids From Lotus Leaves and Their Quantitative Analysis in Dietary Weight Loss Supplements. J Agric Food Chem. 2015 Jun 17;63(23):5634-9.  [Content Brief]

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