Isolimonexic acid

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Isolimonexic acid 

Isolimonexic acid 是从柠檬种子中分离得到的一种类柠檬酸，具有抗癌和抗芳香化酶 (anti-aromatase) (IC50=25.60 μM) 特性。

Isolimonexic acid

Isolimonexic acid Chemical Structure

CAS No. : 73904-93-5

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Isolimonexic acid 相关产品

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生物活性

Isolimonexic acid is a limonoid isolated from lemon (Citrus lemon L. Burm) seed, has anti-cancer and anti-aromatase (IC50=25.60 μM) properties[1].

IC50 & Target

Aromatase

 

体外研究
(In Vitro)

Isolimonexic acid (200 μM; 72 hours) exhibits cytotoxicity on MCF-7 cells and shows no cytotoxicity against the MDA-MB-231 cell lines[1].
Isolimonexic acid (50 μg/ml; 48, 96 and 144 hours) exhibits cell growth inhibition of Panc-28 cells in a time-dependent manner.And it percent inhibition comparison to control cells are 21%, 68%, and 90.58% at 48, 72, and 144 h, respectively[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Isolimonexic acid 相关抗体:
分子量

502.51

Formula

C26H30O10
CAS 号

73904-93-5
结构分类
  • Others
初始来源
  • 植物
  • 芸香科
  • 柠檬
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (542 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Jinhee Kim, et al. Limonoids and their anti-proliferative and anti-aromatase properties in human breast cancer cells. Food Funct. 2013 Feb;4(2):258-65.  [Content Brief]

    [2]. Jaiprakash R Patil, et al.Bioactive compounds from Mexican lime ( Citrus aurantifolia ) juice induce apoptosis in human pancreatic cells. J Agric Food Chem. 2009 Nov 25;57(22):10933-42.  [Content Brief]

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