Verruculogen (Synonyms: 疣孢青霉原)

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Verruculogen (Synonyms: 疣孢青霉原) 纯度: 97.52%

Verruculogen 是一种主要由青霉和曲霉属产生的毒素，在受感染的动物中引起严重震颤。Verruculogen 抑制 Ca²⁺ 激活的 K⁺ 通道。Verruculogen 是哺乳动物细胞周期的 M 期抑制剂。

Verruculogen Chemical Structure

CAS No. : 12771-72-1

规格	价格	是否有货
1 mg	￥3020	In-stock
5 mg	￥7550	In-stock
10 mg		询价
50 mg		询价

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生物活性

Verruculogen is a toxin produced mainly by Penicillium and Aspergillus spp. and causes severe tremors in affected animals. Verruculogen inhibits Ca²⁺-activated K⁺ channels. Verruculogen is an M phase inhibitor of the mammalian cell cycle^[1]^[2]^[3].

分子量

450.33

Formula

C₂₀H₂₄BrN₃O₄

CAS 号

12771-72-1

性状

固体

颜色

White to light brown

中文名称

疣孢青霉原

结构分类

Others

初始来源

微生物

Penicillium verruculosum

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

纯度 & 产品资料

纯度: 97.52%

选择批次：

Data Sheet (528 KB) SDS (420 KB)

COA (265 KB) RP-HPLC (532 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Luciane M. Kawashima, et al. The development of an analytical method for two mycotoxins, patulin and verruculogen, and survey of their presence in commercial tomato pulp. Brazilian Journal of Microbiology

[2]. Knaus HG, et al. Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels. Biochemistry. 1994 May 17;33(19):5819-28. [Content Brief]

[3]. Cui CB, et al. Novel mammalian cell cycle inhibitors, tryprostatins A, B and other diketopiperazines produced by Aspergillus fumigatus. II. Physico-chemical properties and structures. J Antibiot (Tokyo). 1996 Jun;49(6):534-40. [Content Brief]

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