Carlinoside

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Carlinoside 

Carlinoside 是一种具有保肝作用的黄酮类苷类化合物。Carlinoside 能通过 Nrf2 基因表达刺激胆红素-UGT 活性，减少肝脏胆红素积累。Carlinoside 对肝功能障碍所致的高胆红素血症有潜在的干预作用。

Carlinoside

Carlinoside Chemical Structure

CAS No. : 59952-97-5

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生物活性

Carlinoside is a flavone glycoside with hepatoprotective efficiency. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Carlinoside has the potential to intervene hyperbilirubinemia due to liver dysfunction[1].

分子量

580.49

Formula

C26H28O15
CAS 号

59952-97-5
结构分类
  • Flavonoids
  • Flavones
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 禾本科
  • 柠檬草
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (531 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Kundu, et al. Carlinoside reduces hepatic bilirubin accumulation by stimulating bilirubin-UGT activity through Nrf2 gene expression. Biochem Pharmacol. 2011 Nov 1;82(9):1186-97.  [Content Brief]

    [2]. Das S, et al. Impact of edaphic factors and nutrient management on the hepatoprotective efficiency of Carlinoside purified from pigeon pea leaves: An evaluation of UGT1A1 activity in hepatitis induced organelles. Environ Res. 2018 Feb;161:512-523.  [Content Brief]

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