Ganodermanontriol (Synonyms: 灵芝马酮)

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Ganodermanontriol  (Synonyms: 灵芝马酮)

Ganodermanontriol，是从 Ganoderma lucidum 中提取的一种甾醇，通过 HO-1 的表达诱导 t-BHP 损伤肝细胞的抗炎活性。Ganodermanontriol 具有保肝作用。

Ganodermanontriol (Synonyms: 灵芝马酮)

Ganodermanontriol Chemical Structure

CAS No. : 106518-63-2

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Ganodermanontriol 相关产品

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生物活性

Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity[1][2].

体外研究
(In Vitro)

Ganodermanontriol inhibits breast cancer cell lines MCF-7 and MDA-MB-231with IC50 values of 5.8 and 9.7 μM, respectively[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Ganodermanontriol 相关抗体:
分子量

472.70

Formula

C30H48O4
CAS 号

106518-63-2
中文名称

灵芝马酮
结构分类
  • Terpenoids
  • Other Terpenoids
初始来源
  • 植物
  • 多孔菌科
  • 内源性代谢物
  • 人肠道微生物代谢物
  • 微生物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (528 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Ha do T, et al. In vitro and in vivo hepatoprotective effect of ganodermanontriol against t-BHP-induced oxidative stress. Ethnopharmacol. 2013 Dec 12;150(3):875-85.  [Content Brief]

    [2]. Kennedy EM, et al. Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols. J Nat Prod. 2011 Nov 28;74(11):2332-7.  [Content Brief]

    [3]. Jedinak A, Thyagarajan-Sahu A, Jiang J, Sliva D. Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ß-catenin signaling. Int J Oncol. 2011;38(3):761-767.  [Content Brief]

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