Clausine E (Synonyms: Clauszoline I)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Clausine E (Synonyms: Clauszoline I)

Clausine E 是一种生物碱，能够从假黄皮中分离得到，是脂肪量和肥胖相关蛋白去甲基化酶的抑制剂。Clausine E 具有抑制滑膜细胞和肿瘤细胞增殖的活性。

Clausine E Chemical Structure

CAS No. : 182261-83-2

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Clausine E 相关产品

生物活性	Clausine E, is a alkaloid which can be isolated from Clausena excavata, is a inhibitor of fat mass and obesity-associated protein (FTO) demethylase. Clausine E shows inhibitory activities against proliferation of synoviocytes and cancer cells.
分子量	241.24
Formula	C₁₄H₁₁NO₃
CAS 号	182261-83-2
结构分类	Alkaloids
初始来源	植物芸香科越南黄皮
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料	Data Sheet (530 KB) 产品使用指南 (1538 KB)
参考文献	[1]. Wang Y, Li J, Han X, et al. Identification of Clausine E as an inhibitor of fat mass and obesity-associated protein (FTO) demethylase activity. J Mol Recognit. 2019;32(10):e2800. [Content Brief] [2]. Guo JM, Yu XM, Jiang B, et al. Zhongguo Zhong Yao Za Zhi. 2021;46(17):4438-4445. [Content Brief] [3]. Liger F, Popowycz F, Besson T, Picot L, Galmarini CM, Joseph B. Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres. Bioorg Med Chem. 2007;15(16):5615-5619. [Content Brief]

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