Monazomycin is a polyene-like antibiotic produced by Streptomyces. Monazomycin molecular weight is about 1200^[1].

Monazomycin is an antibiotic produced by Streptomyces. Its molecular weight is about 1200, and is related to that of polyene antibiotics. Monazomycin has an amino group that gives a positive charge to the molecule at neutral pH. When monazomycin is added in micromolar amounts to one side of a bilayer, membrane conductance becomes strongly voltage-dependent. Monazomycin is present in the solution in the form of relatively hydrophilic clusters and is adsorbed as such on top of the lipid bilayer, penetration into the bilayer following a potential jump is assumed to be preceded by a potential-independent disaggregation of the adsorbed clusters into adsorbed monomers^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

1364.82

C₇₂H₁₃₃NO₂₂

11006-31-8

• Antibiotics
• Disease Research
• Antibacterial

• Antibiotics
• Other Antibiotics

• 微生物

Streptoverticillium mashuense

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Becucci L, et al. Kinetics of channel formation in bilayer lipid membranes (BLMs) and tethered BLMs: monazomycin and melittin. Langmuir. 2007;23(10):5601-5608.  [Content Brief]