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Laurotetanine (Synonyms: (+)-Laurotetanine)
Laurotetanine ((+)-Laurotetanine) 是一种口服有效的异喹啉类生物碱,可从 Litsea cubeba (Lour.) Pers 的根中提取。Laurotetanine 通过下调 MUC5AC 和 NF-κB 信号通路抑制 IgE、组胺和炎症反应发挥抗哮喘作用。
Laurotetanine Chemical Structure
CAS No. : 128-76-7
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生物活性 |
Laurotetanine ((+)-Laurotetanine) is an potent and orally active isoquinoline alkaloid and could be extracted from the roots of Litsea cubeba (Lour.) Pers. Laurotetanine exerts an anti-asthmatic effect by inhibition of IgE, histamine, and inflammatory reactions via down-regulating MUC5AC and NF-κB signaling pathways[1]. |
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体内研究 (In Vivo) |
Laurotetanine ((+)-Laurotetanine; 20-60 mg/kg; p.o.; 每天,持续 21 天; SD 大鼠) 通过下调 MUC5AC 和 NF-κB 信号通路发挥抗哮喘作用。 Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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分子量 |
327.37 |
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Formula |
C19H21NO4 |
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CAS 号 |
128-76-7 |
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结构分类 |
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初始来源 |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
Please store the product under the recommended conditions in the Certificate of Analysis. |
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纯度 & 产品资料 |
Data Sheet (533 KB) 产品使用指南 (1538 KB)
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参考文献 |
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