Rubropunctamine (Synonyms: 潘红胺)

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Rubropunctamine  (Synonyms: 潘红胺)

Rubropunctamine 是一种红色红曲色素。Rubropunctamine 不仅对细菌有抗菌作用，而且对某些酵母菌和丝状真菌菌株也有抗菌作用。Rubropunctamine 还具有潜在的胚胎毒性和致畸性。

Rubropunctamine (Synonyms: 潘红胺)

Rubropunctamine Chemical Structure

CAS No. : 514-66-9

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Rubropunctamine 相关产品

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生物活性

Rubropunctamine is a redMonascus pigment. Not only Rubropunctamine exerts antibiotic action against bacteria but also against some yeast and filamentous fungi strains. Rubropunctamine has potential embryotoxicity and teratogenicity[1].

体外研究
(In Vitro)

Rubropunctamine (0.32-32 nM; 48 h) inhibits Epstein-Barr virus early antigen (EBV-EA) activation induced by 12-O-tetradecanoylphorbol-13-acetate (TPA), with an IC50 of 433 mol ratio/32 pmol TPA[2].
Rubropunctamine (1 h) exhibits moderate scavenging activity (inhibitory ratio (IR)=1.5) against NO generation by (±)-(E)-methyl-2[(E)-hydroxy-imino]-5-nitro-6-methoxy-3-hexemide (NOR 1) in normal human hepato cells[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Rubropunctamine 相关抗体:
体内研究
(In Vivo)

Rubropunctamine inhibits TPA-induced inflammation in mice, with an ID50 of 0.32 mg/ear[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

353.41

Formula

C21H23NO4
CAS 号

514-66-9
中文名称

潘红胺
结构分类
  • Alkaloids
  • Isoquinoline Alkaloids
初始来源
  • 微生物

Monascus
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (531 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Martinkova L, et al. Biological activity of polyketide pigments produced by the fungus Monascus[J]. Journal of Applied Bacteriology, 1995, 79(6): 609-616.

    [2]. Akihisa T, et, al. Azaphilones, furanoisophthalides, and amino acids from the extracts of Monascus pilosus-fermented rice (red-mold rice) and their chemopreventive effects. J Agric Food Chem. 2005 Feb 9;53(3):562-5.  [Content Brief]

    [3]. Patakova P. Monascus secondary metabolites: production and biological activity. J Ind Microbiol Biotechnol. 2013 Feb;40(2):169-81.  [Content Brief]

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