20-HETE Ethanolamide

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20-HETE Ethanolamide 

20-HETE Ethanolamide 是内源性大麻素类 Anandamide 的代谢产物。20-HETE Ethanolamide 与大鼠脑大麻素 CB1 受体结合，Ki 为 985 nM。

20-HETE Ethanolamide

20-HETE Ethanolamide Chemical Structure

CAS No. : 942069-11-6

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生物活性

20-HETE Ethanolamide is a metabolite of endocannabinoid Anandamide. 20-HETE Ethanolamide binds to the rat brain cannabinoid CB1 receptor with a Ki of 985 nM[1][2].

体外研究
(In Vitro)

The kidney microsomes metabolized anandamide to a single mono-oxygenated product, which was identified as 20-HETE-ethanolamide (EA)[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

20-HETE Ethanolamide 相关抗体:
分子量

363.53

Formula

C22H37NO3
CAS 号

942069-11-6
结构分类
  • Alkaloids
  • Other Alkaloids
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (524 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Sridar C, et al. Anandamide oxidation by wild-type and polymorphically expressed CYP2B6 and CYP2D6. Drug Metab Dispos. 2011;39(5):782-788.  [Content Brief]

    [2]. Snider NT, et al. Anandamide metabolism by human liver and kidney microsomal cytochrome p450 enzymes to form hydroxyeicosatetraenoic and epoxyeicosatrienoic acid ethanolamides. J Pharmacol Exp Ther. 2007;321(2):590-597.  [Content Brief]

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