OMDM-3 is a selective and metabolically stable inhibitor of anandamide cellular uptake (ACU), with a K_i of 16.6 μM^[1].

Ki: 16.6 μM (anandamide cellular uptake)^[1]

OMDM-3 shows poor affinity for either CB1 (K_i=6.1 μM) or CB2 (K_i>10 μM) receptors in rat brain and spleen membranes, respectively. OMDM-3 has almost no activity at vanilloid receptors in the intracellular calcium assay carried out with intact cells over-expressing the human VR1 (EC₅₀>10 μM), and no activity as inhibitors of FAAH in N18TG2 cell membranes (K_i>50 μM)^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

453.66

C₂₉H₄₃NO₃

616884-64-1

• Alkaloids
• Other Alkaloids

• Phenols
• Monophenols

• 内源性代谢物

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Ortar G, et al. Novel selective and metabolically stable inhibitors of anandamide cellular uptake. Biochem Pharmacol. 2003 May 1;65(9):1473-81.  [Content Brief]