Laccase-IN-1

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Laccase-IN-1 

Laccase-IN-1 (compound 4b) 是一种具有口服活性的 laccase 抑制剂，IC50 为 11.3 μM。Laccase-IN-1对苹果 B. dothidea 有保护和治疗作用。Laccase-IN-1 增强 B. dothidea 细胞膜通透性，破坏菌丝表面形态和细胞超微结构，降低麦角甾醇和胞外多糖含量。

Laccase-IN-1

Laccase-IN-1 Chemical Structure

CAS No. : 2991094-41-6

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生物活性

Laccase-IN-1 (compound 4b) is an orally active inhibitor of laccase, with the IC50 of 11.3 μM. Laccase-IN-1displays protective and curative effects on apple fruits infected by B. dothidea. Laccase-IN-1 enhances the cell membrane permeability, destroys the mycelial surface morphology and the cell ultrastructure, and reduces the ergosterol and exopolysaccharide contents of B. dothidea[1].

IC50 & Target

11.3 μM (laccase)[1]
分子量

306.33

Formula

C16H19FN2O3
CAS 号

2991094-41-6
结构分类
  • Others
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (527 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Yang Z, et al. Design, Synthesis, and Biological Evaluation of Novel Camphor-Based Hydrazide and Sulfonamide Derivatives as Laccase Inhibitors against Plant Pathogenic Fungi/Oomycetes. J Agric Food Chem. 2023;71(39):14151-14163.  [Content Brief]

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