Uridine diphosphate glucuronic acid ammonium (Synonyms: UDP-α-D-glucuronic acid ammonium)

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Uridine diphosphate glucuronic acid ammonium  (Synonyms: UDP-α-D-glucuronic acid ammonium)

Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium 是 UDP – 葡萄糖脱氢酶催化活性形成的一种辅助因子。 Uridine diphosphate glucuronic acid (ammonium) 是糖核苷酸生物合成的中心前体，是分别释放 UDP -半乳糖醛酸 (UDP-GalA) 和UDP -戊糖产物的 C4 表聚酶和脱羧酶的共同底物。 Uridine diphosphate glucuronic acid (ammonium) 作为葡萄糖醛酸供体，可用于研究胆红素在内质直肠的结合。

Uridine diphosphate glucuronic acid ammonium (Synonyms: UDP-α-D-glucuronic acid ammonium)

Uridine diphosphate glucuronic acid ammonium Chemical Structure

CAS No. : 43195-60-4

规格 价格 是否有货 数量
25 mg ￥3448 3 – 4 周
50 mg ￥5509 3 – 4 周
100 mg ￥8813 3 – 4 周
200 mg   询价  
500 mg   询价  

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生物活性

Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium is a cofactor that is formed by the catalytic activity of UDP-glucose dehydrogenase. Uridine diphosphate glucuronic acid (ammonium) is a central precursor in sugar nucleotide biosynthesis and common substrate for C4-epimerases and decarboxylases releasing UDP-galacturonic acid (UDP-GalA) and UDP-pentose products, respectively. Uridine diphosphate glucuronic acid (ammonium), as a glucuronic acid donor, can be used for for the research of the conjugation of bilirubin in the endoplasmic recticulum[1].

IC50 & Target

Human Endogenous Metabolite

 

Formula

C15H22N2O18P2.xNH3
CAS 号

43195-60-4
中文名称

尿苷5′-二磷酸葡萄糖醛酸铵盐
结构分类
  • Others
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (535 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Annika J E Borg, et al. Mechanistic characterization of UDP-glucuronic acid 4-epimerase. FEBS J. 2021 Feb;288(4):1163-1178.  [Content Brief]

    [2]. DUTTON GJ. Uridine diphosphate glucuronic acid as glucuronyl donor in the synthesis of ester, aliphatic and steroid glucuronides. Biochem J. 1956 Dec;64(4):693-701.  [Content Brief]

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