Heparin (Synonyms: 肝素)

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Heparin  (Synonyms: 肝素)

Heparin 是硫酸粘多糖，是注射抗凝剂，是负电荷密度最高的生物分子。Heparin 显著抑制外泌体-细胞相互作用。

Heparin (Synonyms: 肝素)

Heparin Chemical Structure

CAS No. : 9005-49-6

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Heparin 相关产品

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•同靶点蛋白产品:

生物活性

Heparin is a highly sulfated glycosaminoglycan,that is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule. Heparin significantly inhibits exosome-cell interactions.

IC50 & Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Heparin (6 天) 可降低 HIV 对 MT-4 细胞的细胞致病性，IC50 为 7.5 μg/mL[2]。
Heparin (0.5 U/mL，48 小时) 抑制 SGHPL-4 细胞系中 HGF 诱导的滋养层侵袭[3]。

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Heparin 相关抗体:
Clinical Trial

CAS 号

9005-49-6
中文名称

肝素；肝磷脂
结构分类
  • Saccharides
  • Polysaccharides
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (543 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Capila I, et al. Heparin-protein interactions. Angew Chem Int Ed Engl. 2002 Feb 1;41(3):391-412.  [Content Brief]

    [2]. Ito M, et al. Inhibitory effect of dextran sulfate and heparin on the replication of human immunodeficiency virus (HIV) in vitro. Antiviral Res. 1987 Jul;7(6):361-7.  [Content Brief]

    [3]. Ganapathy R, et al. Effect of heparin and fractionated heparin on trophoblast invasion. Hum Reprod. 2007 Sep;22(9):2523-7.  [Content Brief]

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