Glicoricone

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Glicoricone  纯度: ≥96.0%

Glicoricone 是一种从甘草中分离出来的酚类化合物。Glicoricone 是单胺氧化酶 (MAO) 的抑制剂,IC50 为 140 μM。Glicoricone 可与雌激素受体 (ER) 结合并显示出雌激素拮抗剂活性。

Glicoricone

Glicoricone Chemical Structure

CAS No. : 161099-37-2

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1 mg ¥3920 In-stock
5 mg ¥9800 In-stock
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Glicoricone 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus

同靶点产品:

同靶点蛋白产品:

生物活性

Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC50 of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity[1][2].

IC50 & Target

IC50: 140 μM (monoamine oxidase)[1]

分子量

368.38

Formula

C21H20O6

CAS 号

161099-37-2

性状

固体

颜色

White to yellow

结构分类
  • Flavonoids
  • Isoflavones
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 豆科
  • 甘草
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥96.0%

Data Sheet (527 KB) SDS (251 KB)

COA (262 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Hatano T, et, al. Phenolic constituents of licorice. III. Structures of glicoricone and licofuranone, and inhibitory effects of licorice constituents on monoamine oxidase. Chem Pharm Bull (Tokyo). 1991 May;39(5):1238-43.  [Content Brief]

    [2]. Boonmuen N, et, al. Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. Steroids. 2016 Jan;105:42-9.  [Content Brief]

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