Icariside D2

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上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Icariside D2  纯度: ≥98.0%

Icariside D2 可从Annona glabra 中分离得到，可抑制血管紧张素转换酶。Icariside 对HL-60 细胞的IC50 值为9.0 ± 1.0 μM。Icariside D2 可诱导凋亡。

Icariside D2

Icariside D2 Chemical Structure

CAS No. : 38954-02-8

规格 价格 是否有货 数量
1 mg ￥4860 In-stock
5 mg   询价  
10 mg   询价  

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Icariside D2 相关产品

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生物活性

Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis [1][2].

体外研究
(In Vitro)

Icariside D2 3 induces apoptosis via alteration of expression of apoptosis-related proteins and decreases phosphorylation of AKT in HL-60 cells[1].
Icariside D2 exhibits anti-inflammatory and anti-HIV activity[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Icariside D2 相关抗体:
分子量

300.30

Formula

C14H20O7
CAS 号

38954-02-8
性状

固体

颜色

White to off-white

结构分类
  • Others
初始来源
  • 植物
  • 番荔枝科
  • 圆滑番荔枝
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥98.0%

Data Sheet (526 KB) SDS (393 KB)

COA (167 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Nguyen Thi Thu Hien, et al. Chemical Constituents of the Annona Glabra Fruit and Their Cytotoxic Activity. Pharm Biol. 2015;53(11):1602-7.  [Content Brief]

    [2]. Xue Liu, et al. Metabolic Engineering Escherichia coli for Efficient Production of Icariside D2. Biotechnol Biofuels. 2019 Nov 6;12:261.  [Content Brief]

    [3]. Jin-YuLi, et al. Three new acylated prenylflavonol glycosides from Epimedium koreanum. Phytochemistry Letters Volume 17, September 2016, Pages 206-212.

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