8-NH2-ATP (Synonyms: 8-Aminoadenosine-5′-O-triphosphate)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
8-NH2-ATP (Synonyms: 8-Aminoadenosine-5′-O-triphosphate)

8-NH2-ATP 是 ATP 的非活性形式，由 8-NH2-Ado 产生。8-NH2-Ado 可诱导凋亡相关的poly (ADP-ribose) 聚合酶裂解。

8-NH2-ATP Chemical Structure

CAS No. : 35874-49-8

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8-NH2-ATP 的其他形式现货产品:

8-NH2-ATP tetrasodium

8-NH2-ATP 相关产品

生物活性	8-NH2-ATP, an inactive form of ATP, is produced by 8-NH2-Ado. 8-NH2-Ado is reported to be potent as shown by induction of apoptosis-related cleavage of poly (ADP-ribose) polymerase^[1]^[2].
体外研究 (In Vitro)	The extensive cellular accumulation of 8-NH2-ATP has an inhibitory effect on both RNA and DNA synthesis in both glucocorticoid-sensitive and glucocorticoid-resistant myeloma cell lines^[1]^[2]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. 8-NH2-ATP 相关抗体:
分子量	522.20
Formula	C₁₀H₁₇N₆O₁₃P₃
CAS 号	35874-49-8
结构分类	Others
初始来源	内源性代谢物
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料	Data Sheet (525 KB) 产品使用指南 (1538 KB)
参考文献	[1]. Nancy L Krett, et al. 8-amino-adenosine is a potential therapeutic agent for multiple myeloma. Mol Cancer Ther. 2004 Nov;3(11):1411-20. [Content Brief] [2]. Yuji Matsuzaki, et al. ATP-association to intrabacterial nanotransportation system in Vibrio cholera. Med Mol Morphol. 2015 Dec;48(4):225-34. [Content Brief]

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