(-)-Integerrimine (Synonyms: 全缘千里光碱)

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(-)-Integerrimine  (Synonyms: 全缘千里光碱)

(-)-Integerrimine 是一种吡咯里西啶生物碱,具有抗溃疡活性。 (-)-Integerrimine 也是果蝇中的致突变剂和弱致裂剂。

(-)-Integerrimine                                          (Synonyms: 全缘千里光碱)

(-)-Integerrimine Chemical Structure

CAS No. : 480-79-5

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(-)-Integerrimine 相关产品

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生物活性

(-)-Integerrimine, a pyrrolizidine alkaloid, has antiulcerogenic activity. (-)-Integerrimine is also a mutagenic and weakly clastogenic agent in Drosophila[1][2].

体外研究
(In Vitro)

(-)-Integerrimine (0.00625-0.05 mM) also must have mutagenic activity in somatic cells of Drosophila. (-)-Integerrimine in general requires cytochrome P450-dependent metabolic activation to exhibit genotoxic activity[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

(-)-Integerrimine 相关抗体:

分子量

335.39

Formula

C18H25NO5

CAS 号

480-79-5

中文名称

全缘千里光碱

结构分类
  • Alkaloids
  • Pyrrole Alkaloids
初始来源
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
Data Sheet (533 KB) 产品使用指南 (1538 KB)

参考文献
  • [1]. V R Campesato, et al. Recombinagenic activity of integerrimine, a pyrrolizidine alkaloid from Senecio brasiliensis, in somatic cells of Drosophila melanogaster. Environ Mol Mutagen. 1997;29(1):91-7.  [Content Brief]

    [2]. Walber Toma, et al. Modulation of gastrin and epidermal growth factor by pyrrolizidine alkaloids obtained from Senecio brasiliensis in acute and chronic induced gastric ulcers. Can J Physiol Pharmacol. 2004 May;82(5):319-25.  [Content Brief]

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