Sophoranol (Synonyms: 槐醇)

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Sophoranol  (Synonyms: 槐醇)

Sophoranol 是一种能从 S. flavescens 中分离得到的生物碱，具有抗病毒活性。Sophoranol 具有抗乙型肝炎病毒 (HBV) 活性。Sophoranol 对呼吸道合胞病毒 (RSV) 具有较强的抗病毒活性，其 IC50 值为 10.4 μg/mL。

Sophoranol (Synonyms: 槐醇)

Sophoranol Chemical Structure

CAS No. : 3411-37-8

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生物活性

Sophoranol is an alkaloid that can be isolated from S. flavescens, with antiviral activity. Sophoranol has anti-HBV (hepatitis B virus) activity. Sophoranol shows potent antiviral activities against respiratory syncytial virus (RSV) with an IC50 of 10.4 μg/mL[1][2].

IC50 & Target

IC50: 10.4 μg/mL (RSV)[2]
体外研究
(In Vitro)

Sophoranol has a remarkable inhibitory effect on the secretion of HBsAg and HBeAg in 2.2.15 cell line[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Sophoranol 相关抗体:
分子量

264.36

Formula

C15H24N2O2
CAS 号

3411-37-8
中文名称

槐醇
结构分类
  • Alkaloids
  • Piperidine Alkaloids
初始来源
  • 植物
  • 豆科
  • 苦参
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (533 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Guan Ye, et al. LC-MS characterization of efficacy substances in serum of experimental animals treated with Sophora flavescens extracts. Biomed Chromatogr. 2007 Jun;21(6):655-60.  [Content Brief]

    [2]. Shuang-Cheng Ma, et al. Antiviral Chinese medicinal herbs against respiratory syncytial virus. J Ethnopharmacol. 2002 Feb;79(2):205-11.  [Content Brief]

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