Euphol acetate

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Euphol acetate 

Euphol acetate 是一种三萜烯类化合物，可以从 Euphorbia broteri 中提取得到。Euphol acetate 是肝转运蛋白 OATP1B1/3 的抑制剂。

Euphol acetate

Euphol acetate Chemical Structure

CAS No. : 13879-04-4

规格 是否有货
5 mg 询价
10 mg 询价
25 mg 询价

* Please select Quantity before adding items.

Euphol acetate 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

Euphol acetate is a triterpene that can be isolated from Euphorbia broteri. Euphol acetate is an inhibitor of hepatic transport proteins organic anion-transporting polypeptide 1/3 (OATP1B1/3)[1][2].

IC50 & Target

OATP1B1/3[2]
体外研究
(In Vitro)

Euphol acetate (10 μM) suppresses the uptake of the OATP1B substrate sodium fluorescein in OATP1B1 (29.2%)- or 1B3 (40.2%)-transfected CHO cells[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Euphol acetate 相关抗体:
分子量

468.75

Formula

C32H52O2
CAS 号

13879-04-4
结构分类
  • Terpenoids
  • Triterpenes
初始来源
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (523 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. DePascual Teresa, et al. Triterpenes from Euphorbia broteri. Phytochemistry. 1987. 26(6): 1767-1776.

    [2]. Tom De Bruyn, et al. Structure-based identification of OATP1B1/3 inhibitors. Mol Pharmacol. 2013 Jun;83(6):1257-67.  [Content Brief]

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务