Catalponol (Synonyms: 梓酚)

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Catalponol  (Synonyms: 梓酚)

Catalponol 是萘醌衍生物。Catalponol 通过诱导酪氨酸羟化酶 (tyrosine hydroxylase) 活性来增强多巴胺的生物合成。Catalponol 还可以提高 PC12 细胞中 cAMP 和酪氨酸羟化酶磷酸化的水平。

Catalponol (Synonyms: 梓酚)

Catalponol Chemical Structure

CAS No. : 34168-56-4

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Catalponol 相关产品

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生物活性

Catalponol is a naphthoquinone derivative. Catalponol enhances dopamine biosynthesis by inducing tyrosine hydroxylase activity. Catalponol also increases the levels of cAMP and tyrosine hydroxylase phosphorylation in PC12 cells[1][2].

体外研究
(In Vitro)

In RAW 264.7 macrophage cells, Catalponol exhibits potent inhibitory effects with an IC50 value of 9.8 µM for inhibiting LPS-induced NO production[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Catalponol 相关抗体:
分子量

230.30

Formula

C15H18O2
CAS 号

34168-56-4
中文名称

梓酚
结构分类
  • Terpenoids
  • Other Terpenoids
初始来源
  • 植物
  • 紫葳科
  • 梓树
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
Data Sheet (528 KB) 产品使用指南 (1538 KB)

参考文献

  • [1]. Hai-Shan Huang, et al. Catalponol enhances dopamine biosynthesis and protects against L-DOPA-induced cytotoxicity in PC12 cells. J Asian Nat Prod Res. 2009 Oct;11(10):867-75.  [Content Brief]

    [2]. Byeong Min Park, et al. Naphthoquinones from Catalpa ovata and their inhibitory effects on the production of nitric oxide. Arch Pharm Res. 2010 Mar;33(3):381-5.  [Content Brief]

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