(-)-Denudatin B (Synonyms: Denudatin B)

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(-)-Denudatin B  (Synonyms: Denudatin B) 纯度: ≥97.0%

(-)-Denudatin B 具有抗血小板作用，通过电压门控和受体调控的Ca2+通道抑制Ca2+内流，从而放松血管平滑肌。(-)-Denudatin B 通过抑制胶原蛋白和凝血酶诱导的磷酸肌苷分解，在高浓度下具有非特异性的抗血小板作用。

(-)-Denudatin B (Synonyms: Denudatin B)

(-)-Denudatin B Chemical Structure

CAS No. : 87402-88-8

规格 价格 是否有货 数量
1 mg ￥1800 In-stock
5 mg ￥4900 In-stock
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生物活性

(-)-Denudatin B is an antiplatelet agent. (-)-Denudatin B relaxed vascular smooth muscle by inhibiting the Ca2+ influx through voltage-gated and receptor-operated Ca2+ channels[1]. And (-)-Denudatin B has nonspecific antiplatelet action

分子量

356.41

Formula

C21H24O5
CAS 号

87402-88-8
性状

油状物

颜色

Colorless to light yellow

结构分类
  • Phenylpropanoids
  • Lignans
初始来源
  • 植物
  • 胡椒科
  • 蒌叶
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料

纯度: ≥97.0%

Data Sheet (528 KB) SDS (252 KB)

COA (194 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Yu SM,et al. Vasorelaxing effect in rat thoracic aorta caused by denudatin B, isolated from the Chinese herb, magnolia fargesii. Eur J Pharmacol. 1990;187(1):39-47.  [Content Brief]

    [2]. Teng CM, et al. Inhibition of thrombin- and collagen-induced phosphoinositides breakdown in rabbit platelets by a PAF antagonist–denudatin B, an isomer of kadsurenone. Thromb Res. 1990;59(1):121-130.  [Content Brief]

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