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Micronomicin sulfate (Synonyms: 硫酸小诺霉素; Gentamicin C2b sulfate; Antibiotic XK-62-2 sulfate; Sagamicin sulfate) 纯度: ≥98.0%
Micronomicin sulfate (Gentamicin C2b sulfate) 是从 Micromonospora 中分离出来的氨基糖苷抗生素 (antibiotic)。Micronomicin sulfate 是一种接近庆大霉素类抗生素的广谱抗生素,对假单胞菌、变形杆菌、肺炎克雷伯菌、沙雷菌等具有高的抑制活性 (MIC=0.001-8.3 μg/ml)。
Micronomicin sulfate Chemical Structure
CAS No. : 66803-19-8
规格 | 价格 | 是否有货 | 数量 |
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50 mg | ¥520 | In-stock | |
100 mg | ¥680 | In-stock | |
200 mg | 询价 | ||
500 mg | 询价 |
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Micronomicin sulfate 相关产品
•相关化合物库:
- Natural Product Library Plus
- Bioactive Compound Library Plus
生物活性 |
Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic isolated from Micromonospora. Micronomicin sulfate is a broad-spectrum antibiotic close to the gentamicin-type antibiotics, exhibits a high activity against Pseudomonas, Proteus, Klebsiella pneumoniae, Serratia, etc (MIC=0.001-8.3 μg/ml)[1][2]. |
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IC50 & Target |
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体外研究 (In Vitro) |
Micronomicin has a potent antibacterial activity, it is active against Staphylococcus aureus FDA 209 P, Staphylococcus aureus with the minimal inhibitory values of 0.01 μg/ml. It is also against Escherichia coli St.M. 589, Baker 2, F 14-BK, and R5/W677 with the minimal inhibitory values of 0.75 μg/ml, 0.3 μg/ml, 0.03 μg/ml and 0.03 μg/ml. And it is active against Pseudomonas aeruginosa strains and lebsiella pneumoniae strains (MICs = 0.03-17.5 μg/ml)[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only. |
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体内研究 (In Vivo) |
Micronomicin sulfate is highly active against various bacterial infections in mice, and has an intravenous acute LD50 in mice of 93 mg/kg[1].Micronomicin sulfate (intravenous injection; 4-100 mg/kg; 30 days) is injected for subacute toxicity study. The wistar rats dies at the dose level of 100 mg/kg (10 out of 30 animals): renal disorders and ataxia. The renal histological disorders occurrs mainly at the dose levels of 25 mg/kg and over[3]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
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Formula |
C20H41N5O7.xH2SO4 |
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CAS 号 |
66803-19-8 |
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性状 |
固体 |
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颜色 |
White to yellow |
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中文名称 |
硫酸小诺霉素;沙加霉素 |
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结构分类 |
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初始来源 |
Micromonospora |
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运输条件 |
Room temperature in continental US; may vary elsewhere. |
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储存方式 |
4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |
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溶解性数据 |
In Vitro:
H2O 中的溶解度 : 50 mg/mL (超声助溶)
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final) This equation is commonly abbreviated as: C1V1 = C2V2
In Vivo:
以下溶解方案,请直接配置工作液。建议现用现配,在短期内尽快用完。 以下溶剂前显示的百分比是指该溶剂在您配制终溶液中的体积占比; 如在配制过程中出现沉淀、析出现象,可以通过加热和/或超声的方式助溶。
动物溶解方案计算器
请输入动物实验的基本信息:
给药剂量 mg/kg 动物的平均体重 g 每只动物的给药体积 μL 动物数量 只 由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
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纯度 & 产品资料 |
纯度: ≥98.0%
Data Sheet (613 KB) SDS (393 KB)
COA (201 KB) HNMR (355 KB) 产品使用指南 (1538 KB) |
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参考文献 |
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