S-(+)-Marmesin (Synonyms: (+)-Marmesin; (S)-Marmesin)

发表于由

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
S-(+)-Marmesin  (Synonyms: (+)-Marmesin; (S)-Marmesin) 纯度: 99.04%

S-(+)-Marmesin 是一种天然的香豆素，具有 COX-2/5-LOX 双重抑制作用。

S-(+)-Marmesin (Synonyms: (+)-Marmesin; (S)-Marmesin)

S-(+)-Marmesin Chemical Structure

CAS No. : 13849-08-6

规格 价格 是否有货 数量
1 mg ￥304 In-stock
5 mg ￥1200 In-stock
10 mg ￥2000 In-stock
25 mg ￥4000 In-stock
50 mg ￥6900 In-stock
100 mg ￥9900 In-stock
200 mg   询价  
500 mg   询价  

* Please select Quantity before adding items.

S-(+)-Marmesin 相关产品

•相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Immunology/Inflammation Compound Library
  • Metabolism/Protease Compound Library
  • Natural Product Library
  • Anti-Aging Compound Library
  • Ferroptosis Compound Library
  • Medicine Food Homology Compound Library
  • Pyroptosis Compound Library
  • Traditional Chinese Medicine Active Compound Library
  • Anti-Pancreatic Cancer Compound Library
  • Lipid Metabolism Compound Library
  • Food-Sourced Compound Library
  • Anti-Colorectal Cancer Compound Library
  • Antidepressant Compound Library
  • Anti-inflammatory Traditional Chinese Medicine Active Compound Library
  • Plant-Sourced Natural Product Library
  • Human Metabolite Library
  • Anti-Prostate Cancer Compound Library
  • Metabolic Enzyme Compound Library
  • Highly Selective Inhibitors Library
  • Multi-Target Compound Library
  • Radioprotector Library

•同靶点产品:

•同靶点蛋白产品:

生物活性

S-(+)-Marmesin is a natural coumarin, exhibiting COX-2/5-LOX dual inhibitory activity.

IC50 & Target

COX-2

 

5-LOX

 

体外研究
(In Vitro)

S-(+)-Marmesin ((+)-marmesin) shows affinity at the recombinant psoralen synthase, with a Km of 1.5 ± 0.5 μM, exceeding the substrate affinities of other enzymes of the CYP71 subfamily involved in plant secondary metabolism[1]. S-(+)-Marmesin ((+)-marmesin) shows COX-2/5-LOX dual inhibitory activity[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

S-(+)-Marmesin 相关抗体:
分子量

246.26

Formula

C14H14O4
CAS 号

13849-08-6
性状

固体

颜色

White to off-white

中文名称

S-(+)-印度枸橘素；S-(+)-异紫花前胡内酯；S-(+)-印度榀椁素；S-(+)-印枳树皮素
结构分类
  • Phenylpropanoids
  • Coumarins
初始来源
  • 植物
  • 唇形科
  • 小叶铃子香
  • 植物
  • 伞形科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
溶解性数据
In Vitro: 

DMSO 中的溶解度 : 2 mg/mL (8.12 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 4.0607 mL 20.3037 mL 40.6075 mL
5 mM 0.8121 mL 4.0607 mL 8.1215 mL
10 mM — — —

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C储存时，请在2年内使用， -20°C储存时，请在1年内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

=

浓度

×

体积

×

分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×

体积 (start)

V1

=

浓度 (final)

C2

×

体积 (final)

V2

扫码获得
动物溶解方案

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只

由于实验过程有损耗，建议您多配一只动物的量

计算结果
工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: 99.04%

Data Sheet (595 KB) SDS (393 KB)

COA (191 KB) LCMS (94 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Larbat R, et al. Molecular cloning and functional characterization of psoralen synthase, the first committed monooxygenase of furanocoumarin biosynthesis. J Biol Chem. 2007 Jan 5;282(1):542-54. Epub 2006 Oct 26.  [Content Brief]

    [2]. Kim JS, et al. Chemical constituents of the root of Dystaenia takeshimana and their anti-inflammatory activity. Arch Pharm Res. 2006 Aug;29(8):617-23.  [Content Brief]

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务