Phallacidin (Synonyms: 羧基二羟鬼笔毒肽)

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Phallacidin (Synonyms: 羧基二羟鬼笔毒肽) 纯度: ≥92.0%

Phallacidin 是蘑菇毒素的鬼笔毒素家族的成员。Phallacidin 结合 F-肌动蛋白。

Phallacidin Chemical Structure

CAS No. : 26645-35-2

规格	价格	是否有货
1 mg	￥8900	In-stock
5 mg		询价
10 mg		询价

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Phallacidin 相关产品

•同靶点产品:

•同靶点蛋白产品:

生物活性

Phallacidin is a member of the phallotoxin family of mushroom toxins. Phallacidin binds F-actin^[1].

分子量

846.90

Formula

C₃₇H₅₀N₈O₁₃S

CAS 号

26645-35-2

性状

固体

颜色

White to off-white

Sequence

Ala-Trp-Leu-Val-{D-Asp}-Cys-{Hyp} (Sulfide bridge: Trp2- Cys6)

Sequence Shortening

AWLV-{D-Asp}-C-{Hyp} (Sulfide bridge: Trp2- Cys6)

中文名称

羧基二羟鬼笔毒肽

结构分类

Ketones, Aldehydes, Acids

初始来源

微生物

Amanita exitialis basidiocarps

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O

Peptide Solubility and Storage Guidelines:

1. Calculate the length of the peptide.

2. Calculate the overall charge of the entire peptide according to the following table:

	Contents	Assign value
Acidic amino acid	Asp (D), Glu (E), and the C-terminal -COOH.	-1
Basic amino acid	Arg (R), Lys (K), His (H), and the N-terminal -NH₂	+1
Neutral amino acid	Gly (G), Ala (A), Leu (L), Ile (I), Val (V), Cys (C), Met (M), Thr (T), Ser (S), Phe (F), Tyr (Y), Trp (W), Pro (P), Asn (N), Gln (Q)	0

3. Recommended solution:

Overall charge of peptide	Details
Negative (<0)	1. Try to dissolve the peptide in water first. 2. If water fails, add NH₄OH (<50 μL). 3. If the peptide still does not dissolve, add DMSO (50-100 μL) to solubilize the peptide.
Positive (>0)	1. Try to dissolve the peptide in water first. 2. If water fails, try dissolving the peptide in a 10%-30% acetic acid solution. 3. If the peptide still does not dissolve, try dissolving the peptide in a small amount of DMSO.
Zero (=0)	1. Try to dissolve the peptide in organic solvent (acetonitrile, methanol, etc.) first. 2. For very hydrophobic peptides, try dissolving the peptide in a small amount of DMSO, and then dilute the solution with water to the desired concentration.

纯度 & 产品资料

纯度: ≥92.0%

选择批次：

Data Sheet (513 KB) SDS (252 KB)

COA (178 KB)

产品使用指南 (1538 KB)

参考文献

[1]. L S Barak, et al. Fluorescence staining of the actin cytoskeleton in living cells with 7-nitrobenz-2-oxa-1,3-diazole-phallacidin. Proc Natl Acad Sci U S A. 1980 Feb;77(2):980-4. [Content Brief]

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