Propionyl-DL-carnitine chloride (Synonyms: 丙酰肉碱氯化物)

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Propionyl-DL-carnitine chloride  (Synonyms: 丙酰肉碱氯化物) 纯度: ≥98.0%

Propionyl-DL-carnitine chloride 是肉碱的衍生物。Propionyl-DL-carnitine chloride 可用于炎症的研究。

Propionyl-DL-carnitine chloride (Synonyms: 丙酰肉碱氯化物)

Propionyl-DL-carnitine chloride Chemical Structure

CAS No. : 18828-58-5

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Propionyl-DL-carnitine chloride 相关产品

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生物活性

Propionyl-DL-carnitine chloride is a carnitine derivative. Propionyl-DL-carnitine chloride can be used for the research of inflammation[1][2][3][4].

体外研究
(In Vitro)

Propionyl-DL-carnitine chloride shows protection to beta-thalassaemic erythrocytes from oxidative stress[1].
Propionyl-DL-carnitine chloride increases production of 14CO2 from [1-14C]pyruvate and increases the rate of formation of acetyl camitine from pyruvate[2].
Propionyl-DL-carnitine chloride allows the endothelial cells to maintain their functionality and regulatory role on vessel activity for a longer time and decreases the formation of oxygen reactive species due to xanthine oxidase activity on hypoxanthine formed by adenine nucleotide catabolism[4].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Propionyl-DL-carnitine chloride 相关抗体:
体内研究
(In Vivo)

Propionyl-DL-carnitine chloride (2 mM/kg; p.o. once daily for 4 weeks) affects plasma and urine total carnitine concentrations of mice[3].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Adult age-matched male C57BL/6 mice[3]
Dosage: 2 mM/kg
Administration: Oral gavage; 2 mM/kg/day for 4 weeks
Result: Increased plasma and urine total carnitine concentrations, but showed no effect on the skeletal muscle carnitine content of mice.

分子量

253.72

Formula

C10H20ClNO4
CAS 号

18828-58-5
性状

固体

颜色

White to off-white

中文名称

丙酰肉碱氯化物
结构分类
  • Others
初始来源
  • 内源性代谢物
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

Methanol 中的溶解度 : 250 mg/mL (985.34 mM; 超声助溶)

DMSO 中的溶解度 : 100 mg/mL (394.14 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.9414 mL 19.7068 mL 39.4135 mL
5 mM 0.7883 mL 3.9414 mL 7.8827 mL
10 mM 0.3941 mL 1.9707 mL 3.9414 mL

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* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

=

浓度

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体积

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分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×

体积 (start)

V1

=

浓度 (final)

C2

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体积 (final)

V2

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动物溶解方案

动物溶解方案计算器
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给药剂量

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由于实验过程有损耗，建议您多配一只动物的量

计算结果
工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: ≥98.0%

Data Sheet (598 KB) SDS (251 KB)

COA (172 KB) HNMR (243 KB) MS (260 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Palmieri L, et al. Protection of beta-thalassaemic erythrocytes from oxidative stress by propionyl carnitine. Int J Tissue React. 1994;16(3):121-9.  [Content Brief]

    [2]. Tassani V, et al. Anaplerotic effect of propionyl carnitine in rat heart mitochondria. Biochem Biophys Res Commun. 1994 Mar 15;199(2):949-53.  [Content Brief]

    [3]. Morand R, et al. Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice. Eur J Nutr. 2014 Sep;53(6):1313-25.  [Content Brief]

    [4]. Bertelli A, et al. Effect of propionyl carnitine on energy charge and adenine nucleotide content of cardiac endothelial cells during hypoxia. Int J Tissue React. 1991;13(1):37-40.  [Content Brief]

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