Lusianthridin

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Lusianthridin  纯度: ≥98.0%

Lusianthridin 是来自 Dendrobium venustum 的天然化合物，具有抗迁移作用。Lusianthridin 通过抑制Src-STAT3 信号，促进c-Myc 的降解。

Lusianthridin

Lusianthridin Chemical Structure

CAS No. : 87530-30-1

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1 mg ￥3200 In-stock
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生物活性

Lusianthridin, a pure compound from Dendrobium venustum, have an anti-migratory effect. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signaling[1].

体外研究
(In Vitro)

Lusianthridin (0-100 μM) inhibits cell viability at concentrations greater than 50 μM in both H460 and H292 cells[1].
Lusianthridin significantly reduces the CSC populations in both H460 and H292 cells of the CSC spheres, with a significant decrease in the size of the H460 CSC spheres by approximately 10%, 63%, and 77% at day 3 at concentration 5, 10, and 20 μM Lusianthridin, respectively[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Lusianthridin 相关抗体:

Cell Viability Assay[1]

Cell Line: The human non-small cell lung cancer cell lines, NCI-H460, and NCI-H292 cells[1]. 0-100 μM.
Concentration: 0-100 μM.
Incubation Time: 24 h.
Result: Caused a significant reduction in terms of cell viability at concentrations greater than 50 μM in both H460 and H292 cells.

分子量

242.27

Formula

C15H14O3
CAS 号

87530-30-1
性状

固体

颜色

White to off-white

结构分类
  • Phenols
  • Polyphenols
  • Others
初始来源
  • 植物
  • 其他科
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料

纯度: ≥98.0%

Data Sheet (526 KB) SDS (251 KB)

COA (263 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Narumol Bhummaphan, et al. Targeting of Lung Cancer Stem Cells via Src-STAT3 Suppression. Phytomedicine. 2019 Sep;62:152932.  [Content Brief]

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