Gitoxin

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Gitoxin  纯度: ≥95.0%

Gitoxin 是 Na+/K+-ATPase 的抑制剂,是Digitoxin 的降解代谢物,因ZOH 基团靠近C-17β 位置,可改善药代动力学和药效学数据。

Gitoxin

Gitoxin Chemical Structure

CAS No. : 4562-36-1

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5 mg ¥6500 In-stock
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Gitoxin 相关产品

相关化合物库:

  • Natural Product Library Plus
  • Bioactive Compound Library Plus
  • Membrane Transporter/Ion Channel Compound Library
  • Natural Product Library
  • Lipid Compound Library
  • Anti-Cardiovascular Disease Compound Library
  • Plant-Sourced Natural Product Library
  • Human Metabolite Library
  • Heterocyclic Compound Library
  • Membrane Protein-targeted Compound Library

同靶点产品:

同靶点蛋白产品:

生物活性

Gitoxin, a Na+/K+-ATPase inhibitor, usually appears as a result of metabolic degradation of Digitoxin, is just the hydroxyl (ZOH) group close to the C-17β position, which changes the pharmacokinetics and pharmacodynamics of these substances considerably[1].

分子量

780.94

Formula

C41H64O14

CAS 号

4562-36-1

性状

固体

颜色

White to off-white

结构分类
  • Steroids
初始来源
  • 植物
  • 玄参科
  • 毛地黄
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥95.0%

Data Sheet (522 KB) SDS (251 KB)

COA (193 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Danijela Krstić, et al. Effects of digoxin and gitoxin on the enzymatic activity and kinetic parameters of Na+/K+-ATPase. J Enzyme Inhib Med Chem. 2004 Oct;19(5):409-15.  [Content Brief]

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