(Rac)-Shikonin (Synonyms: Shikalkin)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
(Rac)-Shikonin (Synonyms: Shikalkin) 纯度: 98.95%

(Rac)-Shikonin (Shikonin) 具有抗肿瘤活性。(Rac)-Shikonin (Shikonin) 通过诱导坏死死亡来绕过癌症耐药性。

(Rac)-Shikonin Chemical Structure

CAS No. : 54952-43-1

规格	价格	是否有货
5 mg	￥250	In-stock
10 mg	￥400	In-stock
50 mg		询价
100 mg		询价

* Please select Quantity before adding items.

(Rac)-Shikonin 相关产品

•相关化合物库:

Natural Product Library Plus
Bioactive Compound Library Plus
Natural Product Library
Anti-Cancer Compound Library
Phenols Library
Anti-Cancer Natural Product Library
Plant-Sourced Natural Product Library
Anti-Drug-Resistant Compound Library

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•同靶点蛋白产品:

生物活性

(Rac)-Shikonin (Shikonin) possesses anti-tumor activity. (Rac)-Shikonin (Shikonin) circumvents cancer agent resistance by induction of a necroptotic death^[1]^[2].

体外研究
(In Vitro)

Shikonin shows a similar potency toward drug-sensitive cancer cell lines (MCF-7 and HEK293) and their drug-resistant lines overexpressing P-glycoprotein, Bcl-2, or Bcl-xL, which account for most of the clinical cancer drug resistance^[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

(Rac)-Shikonin 相关抗体:

分子量

288.30

Formula

C₁₆H₁₆O₅

CAS 号

54952-43-1

性状

固体

颜色

Brown to reddish brown

结构分类

Phenols
Polyphenols

Others

初始来源

植物
其他科

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据

In Vitro:

DMSO 中的溶解度 : 125 mg/mL (433.58 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液

浓度溶剂体积质量	1 mg	5 mg	10 mg

1 mM	3.4686 mL	17.3430 mL	34.6861 mL
5 mM	0.6937 mL	3.4686 mL	6.9372 mL
10 mM	0.3469 mL	1.7343 mL	3.4686 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

摩尔计算器
稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

动物溶解方案计算器

请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

每只动物的给药体积

μL

动物数量

只

由于实验过程有损耗，建议您多配一只动物的量

计算结果

工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: 98.95%

选择批次：

Data Sheet (597 KB) SDS (536 KB)

COA (194 KB) HNMR (262 KB) LCMS (98 KB)

产品使用指南 (1538 KB)

参考文献

[1]. U Sankawa, Antitumor activity of shikonin and its derivatives. Chem Pharm Bull (Tokyo). 1977 Sep;25(9):2392-5. [Content Brief]

[2]. Weidong Han, et al. Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Mol Cancer Ther. 2007 May;6(5):1641-9. [Content Brief]

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(Rac)-Shikonin 相关产品

•相关化合物库:

•同靶点产品:

•同靶点蛋白产品:

(Rac)-Shikonin 相关抗体:

摩尔计算器

稀释计算器