DL-Alanine (Synonyms: DL-丙氨酸; DL-2-Aminopropionic acid)

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DL-Alanine  (Synonyms: DL-丙氨酸; DL-2-Aminopropionic acid) 纯度: ≥99.0%

DL-alanine 是一种具有口服活性的氨基酸,是 L- 和 D-丙氨酸的外消旋化合物。DL-alanine 与硝酸银水溶液一起用于纳米颗粒生成,作为还原剂和封端剂。DL-alanine 可用于 Cu(II)、Zn(II)、Cd(11) 等过渡金属螯合的研究。DL-alanine 是一种甜味剂,与甘氨酸和糖精钠归为一类。DL-alanine 在组织和肝脏之间的葡萄糖-丙氨酸循环中起关键作用。

DL-Alanine                                          (Synonyms: DL-丙氨酸; DL-2-Aminopropionic acid)

DL-Alanine Chemical Structure

CAS No. : 302-72-7

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生物活性

DL-alanine, an orally active amino acid, is the racemic compound of L- and D-alanine. DL-alanine is employed both as a reducing and a capping agent, used with silver nitrate aqueous solutions for the production of nanoparticles. DL-alanine can be used for the research of transition metals chelation, such as Cu(II), Zn(II), Cd(11). DL-alanine, a sweetener, is classed together with glycine and sodium saccharin. DL-alanine plays a key role in the glucose-alanine cycle between tissues and liver[1][2][3][4][5][6].

IC50 & Target

Human Endogenous Metabolite

 

体内研究
(In Vivo)

DL-alanine (2500-10000 mg/kg, 灌胃, 每日一次, 第 6 至 15 天) 对 SD 大鼠无明显致畸性[7]

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

89.09

Formula

C3H7NO2

CAS 号

302-72-7

性状

固体

颜色

White to off-white

中文名称

DL-丙氨酸

结构分类
  • Amino acids
初始来源
  • 内源性代谢物
  • 人肠道微生物代谢物
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
In Vitro: 

H2O 中的溶解度 : 50 mg/mL (561.23 mM; 超声助溶)

DMSO 中的溶解度 : < 1 mg/mL (insoluble or slightly soluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 11.2246 mL 56.1230 mL 112.2460 mL
5 mM 2.2449 mL 11.2246 mL 22.4492 mL
10 mM 1.1225 mL 5.6123 mL 11.2246 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

* 备注:如您选择水作为储备液,请稀释至工作液后,再用 0.22 μm 的滤膜过滤除菌后使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

=

浓度

×

体积

×

分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×

体积 (start)

V1

=

浓度 (final)

C2

×

体积 (final)

V2

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动物溶解方案

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量

计算结果
工作液所需浓度 : mg/mL

该产品水溶性佳,请具体参考实测 水 / PBS / Saline 中的溶解度数据。
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纯度 & 产品资料

纯度: ≥99.0%

Data Sheet (608 KB) SDS (0 KB)

COA (262 KB)

产品使用指南 (1538 KB)

参考文献
  • [1]. Amrallah AH, et al. Mixed ligand complexes of benzimidazole and pyrimidine hydroxy azo dyes with some transition metals and glycine, dl-alanine or dl-leucine. Talanta. 1998 Aug;46(4):491-500.  [Content Brief]

    [2]. Eder José Guidelli, et, al. Synthesis of silver nanoparticles using dl-alanine for ESR dosimetry applications. Radiation Physics and Chemistry. Volume 81, Issue 3, 2012: Pages 301-307.

    [3]. Rashid M, et al. Biosynthesis of Self-Dispersed Silver Colloidal Particles Using the Aqueous Extract of P. peruviana for Sensing dl-Alanine[J]. Isrn Nanotechnology, 2014, 2014:1-7.

    [4]. Tapper DN, et al. Taste stimuli: a behavioral categorization. Science. 1968 Aug 16;161(3842):708-10.  [Content Brief]

    [5]. Yamaguchi M, et al. Terahertz absorption spectra of L-, D-, and DL-alanine and their application to determination of enantiometric composition[J]. Applied Physics Letters, 2005, 86(5): 053903.

    [6]. Yamamoto T, et al. Gustatory reaction time to various sweeteners in human adults. Physiol Behav. 1985 Sep;35(3):411-5.  [Content Brief]

    [7]. Wang Y, et al. Study on teratogenicity of DL-alanine in SD rats. Journal of Food Safety and Quality. 2021, 2095-0381.

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