Valnemulin-d6 TFA is the deuterium labeled Valnemulin TFA. Valnemulin TFA is a pleuromutilin antibiotic which inhibits protein synthesis in bacteria by binding the peptidyl transferase enzyme in the 50s ribosomal subunit^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

684.88

C₃₃H₄₇D₆F₃N₂O₇S

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

  [2]. L. Stipkovits, et al. The efficacy of valnemulin (Econor®) in the control of disease caused by experimental infection of calves with Mycoplasma bovis. Research in Veterinary Science, Volume 78, Issue 3, June 2005, Pages 207–215.