Plantanone B (Synonyms: Kaempferol 3-O-rhamnosylgentiobioside)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物,专注于信号通路和疾病研究领域。
Plantanone B  (Synonyms: Kaempferol 3-O-rhamnosylgentiobioside)

Plantanone B 是一种中等抗氧化剂,IC50 为 169.8±5.2 μM。Plantanone B 具有显著的绵羊 COX-1 抑制活性和中等的 COX-2 抑制活性。Plantanone B 有研究炎症相关疾病的潜力。

Plantanone B                                          (Synonyms: Kaempferol 3-O-rhamnosylgentiobioside)

Plantanone B Chemical Structure

CAS No. : 55780-30-8

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Plantanone B 相关产品

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生物活性

Plantanone B is a moderate antioxidant-agent with an IC50 of 169.8±5.2 μM. Plantanone B shows significant ovine COX-1 and moderate COX-2 inhibitory activities. Plantanone B has the potential for inflammation-related diseases research[1].

IC50 & Target[1]

Ovine COX-1

21.78±0.2 μM (IC50)

Ovine COX-2

44.01±0.42 μM (IC50)

体外研究
(In Vitro)

The antioxidant activity of Plantanone B is measured by the DPPH method. Plantanone B exhibits a moderate antioxidant activity, with an IC50 value of 169.8±5.2 μM[1].
Plantanone B inhibits COX-1 preferentially over COX-2 with selectivity index (SI) value of 0.49. It shows significant inhibitory activities against ovine COX-1 and COX-2 at concentration of 50 μM, with the inhibition of 76.18% and 21.78%, respectively[1].
.Plantanone B shows significant COX-1 and moderate COX-2 inhibitory activities with IC50 values of 21.78±0.20 μM for COX-1, as well as 44.01±0.42 μM for COX-2, respectively[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Plantanone B 相关抗体:

分子量

756.66

Formula

C33H40O20

CAS 号

55780-30-8

结构分类
  • Flavonoids
  • Flavonols
  • Phenols
  • Polyphenols
初始来源
  • 植物
  • 山茶科
  • 油茶
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
Data Sheet (533 KB) 产品使用指南 (1538 KB)

参考文献
  • [1]. Jun-Wei He, et al. Anti-inflammatory and antioxidant activities of flavonoids from the flowers of Hosta plantaginea RSC Adv., 2018, 8, 18175-18179

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