Xanthopterin hydrate (Synonyms: 黄蝶呤水合物)

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Xanthopterin hydrate  (Synonyms: 黄蝶呤水合物) 纯度: ≥98.0%

Xanthopterin hydrate，一种非共轭的蝶啶化合物，是东方大黄蜂翅膀中黄色颗粒的主要成分，在 386/456 nm 处产生特征性的激发光最大值。 Xanthopterin hydrate (XPT) 引起大鼠肾脏生长和肥大。 Xanthopterin hydrate 抑制 RNA 合成。

Xanthopterin hydrate (Synonyms: 黄蝶呤水合物)

Xanthopterin hydrate Chemical Structure

CAS No. : 5979-01-1

规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥550 In-stock
100 mg ￥500 In-stock
200 mg   询价  
500 mg   询价  

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Xanthopterin hydrate 相关产品

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生物活性

Xanthopterin hydrate, an unconjugated pteridine compound, is the main component of the yellow granule in the Oriental hornet bear wings, produces a characteristic excitation/emission maximum at 386/456 nm[2]. Xanthopterin hydrate(XPT) causes renal growth and hypertrophy in rat[1]. Xanthopterin hydrate inhibits RNA synthesis[4].

体外研究
(In Vitro)

Xanthopterin (7.8-250 mM; 24 hours) show a significant reduction in mitochondrial activity with respect to controls (IC50=109 mM)[2].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

Xanthopterin hydrate 相关抗体:

Cell Viability Assay[2]

Cell Line: MCF-7 cells
Concentration: 7.8 mM-250 mM
Incubation Time: 24 hours
Result: Resulted in a reduction in mitochondrial activity.

分子量

197.15

Formula

C6H7N5O3
CAS 号

5979-01-1
性状

固体

颜色

Light yellow to yellow

结构分类
  • Alkaloids
初始来源
  • 动物

the yellow granule in the Oriental hornet bear wings
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
溶解性数据
In Vitro: 

DMSO 中的溶解度 : 5 mg/mL (25.36 mM; 超声助溶 (<80°C); 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 5.0723 mL 25.3614 mL 50.7228 mL
5 mM 1.0145 mL 5.0723 mL 10.1446 mL
10 mM 0.5072 mL 2.5361 mL 5.0723 mL

查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 2 years; -20°C, 1 year。-80°C储存时，请在2年内使用， -20°C储存时，请在1年内使用。

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量

=

浓度

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体积

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分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×

体积 (start)

V1

=

浓度 (final)

C2

×

体积 (final)

V2

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动物溶解方案

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

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动物的平均体重

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每只动物的给药体积

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动物数量

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由于实验过程有损耗，建议您多配一只动物的量

计算结果
工作液所需浓度 : mg/mL

纯度 & 产品资料

纯度: ≥98.0%

Data Sheet (602 KB) SDS (393 KB)

COA (195 KB) HNMR (242 KB)

产品使用指南 (1538 KB)

参考文献

  • [1]. Xanthopterin (XPT), an unconjugated pteridine compound, affects cell growth and differentiation. When injected into rats, XPT has caused changes that have been interpreted as renal growth and hypertrophy.  [Content Brief]

    [2]. Lord JL, et al. Cytotoxicity of xanthopterin and isoxanthopterin in MCF-7 cells. Cancer Lett. 2005 May 10;222(1):119-24.  [Content Brief]

    [3]. Plotkin M, et al. Xanthopterin in the Oriental hornet (Vespa orientalis): light absorbance is increased with maturation of yellow pigment granules. Photochem Photobiol. 2009 Jul-Aug;85(4):955-61.  [Content Brief]

    [4]. Ziegler I, et al. Pterins and the regulation of lymphocyte activation on the mode of xanthopterin action. Hoppe Seylers Z Physiol Chem. 1984 Jun;365(6):667-73.  [Content Brief]

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