Triamcinolone acetonide-d6

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Triamcinolone acetonide-d6 

Triamcinolone acetonide-d6 是 Triamcinolone acetonide 氘代物。Triamcinolone acetonide 的有效性是 prednisone 的八倍。

Triamcinolone acetonide-d6

Triamcinolone acetonide-d6 Chemical Structure

CAS No. : 352431-33-5

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生物活性

Triamcinolone acetonide-d6 is deuterium labeled Triamcinolone acetonide.

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

440.53

Formula

C24H25D6FO6

CAS 号

352431-33-5

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. http://en.wikipedia.org/wiki/Triamcinolone_acetonide

    [2]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [3]. Zhen Xiang, et al. Glucocorticoids improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels. Int J Biol Sci 2020; 16(13):2382-2391.

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