Tamarixetin-d3(Synonyms: 4′-O-Methyl Quercetin-d3)

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Tamarixetin-d3 (Synonyms: 4′-O-Methyl Quercetin-d3)

Tamarixetin-d3 (4′-O-Methyl Quercetin-d3) 是 Tamarixetin 的氘代物。Tamarixetin (4′-O-Methyl Quercetin) 是槲皮素的天然类黄酮衍生物，具有抗氧化、抗炎作用。Tamarixetin 可以防止心肌肥厚。

Tamarixetin-d3(Synonyms: 4

Tamarixetin-d3 Chemical Structure

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生物活性

Tamarixetin-d3 (4′-O-Methyl Quercetin-d3) is the deuterium labeled Tamarixetin. Tamarixetin (4′-O-Methyl Quercetin) is a natural flavonoid derivative of quercetin, with anti-oxidative and anti-inflammatory effects. Tamarixetin protects against cardiac hypertrophy[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

319.28

Formula

C16H9D3O7
中文名称

柽柳黄素 d3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献

  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Fan C, et al. Tamarixetin protects against cardiac hypertrophy via inhibiting NFAT and AKT pathway. J Mol Histol. 2019 Aug;50(4):343-354.

    [3]. Park HJ, et al. Tamarixetin Exhibits Anti-inflammatory Activity and Prevents Bacterial Sepsis by Increasing IL-10 Production. J Nat Prod. 2018 Jun 22;81(6):1435-1443.

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