Sodium 2-oxopropanoate-13C3(Synonyms: Sodium pyruvate-13C3)

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Sodium 2-oxopropanoate-13C3 (Synonyms: Sodium pyruvate-13C3)

Sodium 2-oxopropanoate-13C3 (Sodium pyruvate-13C3) 是一种 13C 标记的 Sodium 2-oxopropanoate。Sodium 2-oxopropanoate (Sodium pyruvate),葡萄糖的三碳代谢物,是一种在糖酵解途径中产生的化合物。Sodium 2-oxopropanoate是一种可以清除 ROS 的自由基清除剂。

Sodium 2-oxopropanoate-13C3(Synonyms: Sodium pyruvate-13C3)

Sodium 2-oxopropanoate-13C3 Chemical Structure

CAS No. : 142014-11-7

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生物活性

Sodium 2-oxopropanoate-13C3 (Sodium pyruvate-13C3) is the 13C-labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

113.02

Formula

13C3H3NaO3

CAS 号

142014-11-7

中文名称

丙酮酸钠 13C3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. S Nemoto, et al. Role for mitochondrial oxidants as regulators of cellular metabolism. Mol Cell Biol. 2000 Oct;20(19):7311-8.

    [3]. W Zhao, et al. Fructose induced deactivation of antioxidant enzymes: preventive effect of pyruvate. Free Radic Res. 2000 Jul;33(1):23-30.

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