Tetrahydrofolic acid-d4(Synonyms: 四氢叶酸 d4)

上海金畔生物科技有限公司为生命科学和医药研发人员提供生物活性分子抑制剂、激动剂、特异性抑制剂、化合物库、重组蛋白、同位素标记物，专注于信号通路和疾病研究领域。
Tetrahydrofolic acid-d4 (Synonyms: 四氢叶酸 d4)

Tetrahydrofolic acid-d4 (L-5,6,7,8-Tetrahydrofolic acid-d4) 是 Tetrahydrofolic acid 的氘代物。Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) 是一种具有生物活性的维生素 B9 叶酸衍生物，是氨基酸，核酸和脂质的一个碳原子的供体。Tetrahydrofolic acid 用作游离甲醛的受体，产生 5,10-亚甲基四氢叶酸-四氢叶酸。

Tetrahydrofolic acid-d4 Chemical Structure

CAS No. : 1356841-72-9

规格		是否有货
1 mg		Check price and availability

* Please select Quantity before adding items.

生物活性	Tetrahydrofolic acid-d4 (L-5,6,7,8-Tetrahydrofolic acid-d4) is the deuterium labeled Tetrahydrofolic acid. Tetrahydrofolic acid (L-5,6,7,8-Tetrahydrofolic acid) is the biologically active vitamin B9 folate derivative. Tetrahydrofolic acid is a donor of one-carbon groups for amino acids, nucleic acids, and lipids. Tetrahydrofolic acid serves as an acceptor of free formaldehyde, producing 5,10-methylenetetrahydrofolate-Tetrahydrofolic acid^[1]^[2].
体外研究 (In Vitro)	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1]. Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.
分子量	449.45
Formula	C₁₉H₁₉D₄N₇O₆
CAS 号	1356841-72-9
中文名称	四氢叶酸 d4
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.
参考文献	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Clara B García-Calderón, et al. Genotoxicity of Tetrahydrofolic Acid to Hematopoietic Stem and Progenitor Cells. Cell Death Differ. 2018 Nov;25(11):1967-1979.

所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务