(S)-Malic acid-d3(Synonyms: (S)-Hydroxybutanedioic acid-d3; (S)-E 296-d3)

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(S)-Malic acid-d3 (Synonyms: (S)-Hydroxybutanedioic acid-d3; (S)-E 296-d3)

(S)-Malic acid-d3 ((S)-Hydroxybutanedioic acid-d3) 是 (S)-Malic acid 的氘代物。(S)-Malic acid ((S)-2-Hydroxysuccinic acid) 是一种天然存在的二羧酸,水果酸甜味的来源,常用作食品添加剂。

(S)-Malic acid-d3(Synonyms: (S)-Hydroxybutanedioic acid-d3;  (S)-E 296-d3)

(S)-Malic acid-d3 Chemical Structure

CAS No. : 59652-74-3

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生物活性

(S)-Malic acid-d3 ((S)-Hydroxybutanedioic acid-d3) is the deuterium labeled (S)-Malic acid. (S)-Malic acid ((S)-2-Hydroxysuccinic acid) is a dicarboxylic acid in naturally occurring form, contributes to the pleasantly sour taste of fruits and is used as a food additive[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

137.11

Formula

C4H3D3O5

CAS 号

59652-74-3

中文名称

(S)-L-苹果酸 d3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Landete JM, et al. Requirement of the Lactobacillus casei MaeKR two-component system for L-malic acid utilization via a malic enzyme pathway. Appl Environ Microbiol. 2010 Jan;76(1):84-95.

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