Cytosine-2,4-13C2-1,3-15N2(Synonyms: 胞嘧啶 2,4-13C2-1,3-15N2)

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Cytosine-2,4-13C2-1,3-15N2 (Synonyms: 胞嘧啶 2,4-13C2-1,3-15N2)

Cytosine-2,4-13C2-1,3-15N2 是一种 13C 和 15N 标记的 Cytosine。Cytosine 是 DNA 和 RNA 中发现的四个主要碱基之一。Cytosine 修饰表现出与表观遗传多样性和衰老有关的昼夜节律振荡。

Cytosine-2,4-13C2-1,3-15N2(Synonyms: 胞嘧啶 2,4-13C2-1,3-15N2)

Cytosine-2,4-13C2-1,3-15N2 Chemical Structure

CAS No. : 285978-06-5

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生物活性

Cytosine-2,4-13C2-1,3-15N2 is the 13C-labeled and 15N-labeled Cytosine. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

Shanghai Jinpan Biotech Co Ltd has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

116.07

Formula

C213C2H515N3O

CAS 号

285978-06-5

中文名称

胞嘧啶 2,4-13C2-1,3-15N2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

    [2]. Maxam AM, et, al. A new method for sequencing DNA. Proc Natl Acad Sci U S A. 1977 Feb;74(2):560-4.

    [3]. Oh G, et, al. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Nat Commun. 2018 Feb 13;9(1):644.

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